K-RITH and Africa Centre have joined to form a new interdisciplinary institute, called the Africa Health Research Institute. Click here to read more.

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K-Rith

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K-RITH conducts cutting-edge scientific research on TB and HIV and aims to translate the findings into new tools to control these diseases.

Research

In late stage infection TB becomes a macrophage ‘serial killer’

Using cutting edge technologies, Africa Health Research Institute (AHRI) scientists have discovered the mechanism which Mycobacterium tuberculosis (M.tb) uses to break down host defences in late stage infection. In a paper published in eLife, researchers for the first time show how M.tb turns lung granulomas, usually tasked with controlling TB infection, against the body. Mycobacterium

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General

The art of science: AHRI hosts an exhibition of the Wellcome Image Awards 2017

Twenty-two of the world’s most incredible science images are on display at the Africa Health Research Institute (AHRI) in Durban for the next month. The Wellcome Image Awards 2017 showcase the best in science image making, and include a broad range of cutting-edge artistic and scientific techniques. From photography and illustration to super-resolution microscopy and

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Our Scientists

Adrie Steyn

STEYN LAB

The main goal of the Steyn Lab’s research is to understand the mechanisms whereby Mycobacterium tuberculosis persist for decades without causing disease, to then suddenly explode.

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Al Leslie

LESLIE LAB

The Leslie Lab investigates the innate immune response to HIV and TB and how novel aspects of this response may potentially be exploited to improve patient outcomes.

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Alex Sigal

SIGAL LAB

The aim of the Sigal Lab is to understand HIV and TB transmission between cells and how it affects the persistence of infection, sensitivity to drugs, rate of the infection cycle and, for HIV, the formation of a quasispecies.

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Alexander Pym

PYM LAB

The Pym Lab focusses on understanding how the TB bacterium is able to tolerate or resist antibiotics.

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Frederick Balagaddé

BALAGADDE LAB

The Balagaddé lab hosts the first microfluidic chip-making foundry in Africa. They are developing medical microchip systems to help control the HIV and TB co-epidemic in South Africa and beyond.

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Thumbi Ndung'u

NDUNG'U LAB

The goal of the Ndung’u laboratory is to understand immune mechanisms against HIV and tuberculosis, and pathogen evasion of immune responses as a pathway to vaccine development.

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NEWS | General

The art of science: AHRI hosts an exhibition of the Wellcome Image Awards 2017

Twenty-two of the world’s most incredible science images are on display at the Africa Health Research Institute (AHRI) in Durban for the next month. The Wellcome Image Awards 2017 showcase the best in science image making, and include a broad range of cutting-edge artistic and scientific techniques. From photography and illustration to super-resolution microscopy and

READ MORE
NEWS | Research

Resistance not an immediate threat to test and treat roll-out

Data from a large Africa Health Research Institute (AHRI) clinical trial shows that high levels of HIV drug resistance are emerging, but do not immediately pose a threat in the context of current first-line drug therapies. The findings were presented at the recent Conference on Retroviruses and Opportunistic Infections (CROI) 2017 in Seattle, USA. The

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NEWS | Research

In late stage infection TB becomes a macrophage ‘serial killer’

Using cutting edge technologies, Africa Health Research Institute (AHRI) scientists have discovered the mechanism which Mycobacterium tuberculosis (M.tb) uses to break down host defences in late stage infection. In a paper published in eLife, researchers for the first time show how M.tb turns lung granulomas, usually tasked with controlling TB infection, against the body. Mycobacterium

READ MORE

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