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K-Rith

K-RITH

Publications

10.08.16

Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

Dirk A. Lamprecht, Peter M. Finin, Md. Aejazur Rahman, Bridgette M. Cumming, Shannon L. Russell, Surendranadha R. Jonnala, John H. Adamson & Adrie J. C. Steyn

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11.04.16

Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance.

Desjardins, C. A., Cohen, K. A., Munsamy, V., Abeel, T., Maharaj, K., Walker, B. J., Shea, T. P., Almeida, D. V., Manson, A. L., Salazar, A., Padayatchi, N., O'Donnell, M. R., Mlisana, K. P., Wortman, J., Birren, B. W., Grosset, J., Earl, A. M., & Pym, A. S.

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07.02.16

Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression.

Kloverpris, H. N., Kazer, S. W., Mjosberg, J., Mabuka, J. M., Wellmann, A., Ndhlovu, Z., Yadon, M. C., Nhamoyebonde, S., Muenchhoff, M., Simoni, Y., Andersson, F., Kuhn, W., Garrett, N., Burgers, W. A., Kamya, P., Pretorius, K., Dong, K., Moodley, A., Newell, E. W., Kasprowicz, V., Abdool Karim, S. S., Goulder, P., Shalek, A. K., Walker, B. D., Ndung'u, T., & Leslie, A.

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01.02.16

Bedaquiline in the treatment of multidrug- and extensively drug-resistant tuberculosis.

Pym, A. S., Diacon, A. H., Tang, S.-J., Conradie, F., Danilovits, M., Chuchottaworn, C., Vasilyeva, I., Andries, K., Bakare, N., De Marez, T., Haxaire-Theeuwes, M., Lounis, N., Meyvisch, P., Van Baelen, B., van Heeswijk, R. P. G., & Dannemann, B.

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26.01.16

Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis

Saini, V., Cumming, B. M., Guidry, L., Lamprecht, D. A., Adamson, J. H., Reddy, V. P., Chinta, K. C., Mazorodze, J. H., Glasgow, J. N., Richard-Greenblatt, M., Gomez-Velasco, A., Bach, H., Av-Gay, Y., Eoh, H., Rhee, K., & Steyn, A. J.

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20.01.16

Assessing the utility of Xpert® MTB/RIF as a screening tool for patients admitted to medical wards in South Africa.

Heidebrecht, C. L., Podewils, L. J., Pym, A. S., Cohen, T., Mthiyane, T., & Wilson, D.

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24.12.15

Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study

Byrne EH, Anahtar MN, Cohen KE, Moodley A, Padavattan N, Ismail N, Bowman BA, Olson GS, Mabhula A, Leslie A, Ndung’u T, Walker BD, Ghebremichael MS, Dong KL, Kwon DS.

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17.11.15

Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa.

Angelique Hölzemer, C. T., Camilo A. Jimenez Cruz, Wilfredo F. Garcia-Beltran, Jonathan M. Carlson, Nienke van Teijlingen, Jaclyn Mann, Manjeetha Jaggernath, Seung-gu Kang, Christian Körner, Amy Chung, Jamie L. Schafer, David T. Evans, Galit Alter, Bruce D. Walker, Philip J. Goulder, Mary Carrington, Pia Hartmann, Thomas Pertel, Ruhong Zhou, Thumbi Ndung’u, Marcus Altfeld.

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01.11.15

Host-Directed Therapies for Tackling Multi-Drug Resistant Tuberculosis: Learning From the Pasteur-Bechamp Debates.

Zumla, Maeurer; Host-Directed Therapies Network (HDT-NET) Consortium; Host-Directed Therapies Network HDT-NET Consortium.

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19.10.15

The effect of SLCO1B1 polymorphisms on the pharmacokinetics of rifabutin in African HIV-infected patients with tuberculosis.

Hennig, S., Naiker, S., Reddy, T., Egan, D., Kellerman, T., Wiesner, L., Owen, A., McIlleron, H., & Pym, A.

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08.10.15

Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus

Pichulik, T., Khatamzas, E., Liu, X., Brain, O., Delmiro Garcia, M., Leslie, A., Danis, B., Mayer, A., Baban, D., Ragoussis, J., Weber, A. N., & Simmons, A. Eur J Immunol.

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29.09.15

Evolution of Extensively Drug-Resistant Tuberculosis over Four Decades: Whole Genome Sequencing and Dating Analysis of Mycobacterium tuberculosis Isolates from KwaZulu-Natal.

Cohen, K. A., Abeel, T., Manson McGuire, A., Desjardins, C. A., Munsamy, V., Shea, T. P., Walker, B. J., Bantubani, N., Almeida, D. V., Alvarado, L., Chapman, S. B., Mvelase, N. R., Duffy, E. Y., Fitzgerald, M. G., Govender, P., Gujja, S., Hamilton, S., Howarth, C., Larimer, J. D., Maharaj, K., Pearson, M. D., Priest, M. E., Zeng, Q., Padayatchi, N., Grosset, J., Young, S. K., Wortman, J., Mlisana, K. P., O'Donnell, M. R., Birren, B. W., Bishai, W. R., Pym, A. S., & Earl, A. M.

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18.09.15

Regulation of Ergothioneine Biosynthesis and Its Effect on Mycobacterium tuberculosis Growth and Infectivity.

Richard-Greenblatt, M., Bach, H., Adamson, J., Pena-Diaz, S., Li, W., Steyn, A. J., & Av-Gay, Y.

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15.09.15

Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point.

Ndhlovu, Z. M., Kamya, P., Mewalal, N., Kloverpris, H. N., Nkosi, T., Pretorius, K., Laher, F., Ogunshola, F., Chopera, D., Shekhar, K., Ghebremichael, M., Ismail, N., Moodley, A., Malik, A., Leslie, A., Goulder, P. J., Buus, S., Chakraborty, A., Dong, K., Ndung'u, T., & Walker, B. D.

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15.09.15

HIV Disrupts Human T Cells That Target Mycobacterial Glycolipids.

Kasprowicz, V. O., Cheng, T. Y., Ndung'u, T., Sunpath, H., Moody, D. B., & Kasmar, A. G. J

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28.08.15

Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor.

Gornalusse, G. G., Mummidi, S., Gaitan, A. A., Jimenez, F., Ramsuran, V., Picton, A., Rogers, K., Manoharan, M. S., Avadhanam, N., Murthy, K. K., Martinez, H., Molano Murillo, A., Chykarenko, Z. A., Hutt, R., Daskalakis, D., Shostakovich-Koretskaya, L., Abdool Karim, S., Martin, J. N., Deeks, S. G., Hecht, F., Sinclair, E., Clark, R. A., Okulicz, J., Valentine, F. T., Martinson, N., Tiemessen, C. T., Ndung'u, T., Hunt, P. W., He, W., & Ahuja, S. K.

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21.08.15

Confinement-Induced Drug-Tolerance in Mycobacteria Mediated by an Efflux Mechanism

Brilliant B. Luthuli, Georgiana E. Purdy, Frederick K. Balagaddé

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12.08.15

Completeness and Reliability of the Republic of South Africa National Tuberculosis (TB) Surveillance System.

Podewils, L. J., Bantubani, N., Bristow, C., Bronner, L. E., Peters, A., Pym, A., & Mametja, L. D.

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25.07.15

Evidence for the presence of clofazimine and its distribution in the healthy mouse brain.

Baijnath S1, Naiker S, Shobo A, Moodley C, Adamson J, Ngcobo B, Bester LA, Singh S, Kruger HG, Naicker T, Govender T.

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