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K-Rith

K-RITH

Publications

17.03.15

High frequency of transmitted HIV-1 Gag HLA class I-driven immune escape variants but minimal immune selection over the first year of clade C infection

Kamini Gounder, Nagavelli Padayachi, Jaclyn K. Mann, Mopo Radebe, Mammekwa Mokgoro, Mary van der Stok, Lungile Mkhize, Zenele Mncube, Manjeetha Jaggernath, Tarylee Reddy, Bruce D. Walker and Thumbi Ndung’u

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17.03.15

Co-infection with Mycobacterium tuberculosis impairs HIV-specific CD8+ and CD4+ T cell functionality

Shivan Chetty, Pamla Govender, Jennifer Zupkosky,Mona Pillay, Musie Ghebremichael,Mahomed-Yunus S Moosa, Thumbi Ndung’u, Filippos Porichis, Victoria O. Kasprowicz

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10.03.15

Latent and Active Tuberculosis Infection Increase Immune Activation in Individuals Co-Infected with HIV

Sullivan, Z. A., Wong, E. B., Ndung'u, T., Kasprowicz, V. O., & Bishai, W. R.

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10.03.15

Latent and Active TB Infection Increase Immune Activation in Individuals Co-Infected with HIV

Zuri A. Sullivan, Emily B. Wong, Thumbi Ndung’u, Victoria O. Kasprowicz, William R. Bishai

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09.03.15

Pharmacokinetics and pharmacodynamics of clofazimine in a mouse model of tuberculosis.

Rosemary V. Swanson, John Adamson, Chivonne Moodley, Bongani Ngcobo, Nicole C. Ammerman, Afton Dorasamy, Sashen Moodley, Zinhle Mgaga, Asa Tapley, Linda A. Bester, Sanil Singh, Jacques H. Grosset, and Deepak V. Almeida

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05.03.15

High Expression of CD26 Accurately Identifies Human Bacterial-Reactive MR1-restricted MAIT cells

Prabhat K. Sharma, Emily B. Wong, Ruth J. Napier, William R. Bishai, Thumbi Ndung’u, Victoria O. Kasprowicz, Deborah A. Lewinsohn, David M. Lewinsohn, Marielle C. Gold

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05.03.15

Comparative Genomics of Cluster O Mycobacteriophages

Cresawn SG, Pope WH, Jacobs-Sera D, Bowman CA, Russell DA, Dedrick RM, Adair T, Anders KR, Ball S, Bollivar D, Breitenberger C, Burnett SH, Butela K, Byrnes D, Carzo S, Cornely KA, Cross T, Daniels RL, Dunbar D, Findley AM, Gissendanner CR, Golebiewska UP, Hartzog GA, Hatherill JR, Hughes LE, Jalloh CS, De Los Santos C, Ekanem K, Khambule SL, King RA, King-Smith C, Klyczek K, Krukonis GP, Laing C, Lapin JS, Lopez AJ, Mkhwanazi SM, Molloy SD, Moran D, Munsamy V, Pacey E, Plymale R, Poxleitner M, Reyna N, Schildbach JF, Stukey J, Taylor SE, Ware VC, Wellmann AL, Westholm D, Wodarski D, Zajko M, Zikalala TS, Hendrix RW, Hatfull GF

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05.03.15

Effective anti-tuberculosis therapy correlates with plasma small RNA.

Honeyborne, I., Lipman, M. C., Eckold, C., Evangelopoulos, D., Gillespie, S. H., Pym, A., & McHugh, T. D.

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20.02.15

A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.

Kloverpris, H. N., Cole, D. K., Fuller, A., Carlson, J., Beck, K., Schauenburg, A. J., Rizkallah, P. J., Buus, S., Sewell, A. K., & Goulder, P.

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26.01.15

Characterization of mouse models of Mycobacterium avium complex infection and evaluation of drug combinations.

Claire Andréjak, Deepak V. Almeida, Sandeep Tyagi, Paul J. Converse, Nicole C. Ammerman, and Jacques H. Grosset

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24.01.15

HIV-1 vaccine immunogen design strategies

Jaclyn K. Mann and Thumbi Ndung’u

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20.01.15

Clofazimine shortens the duration of the first-line treatment regimen for experimental chemotherapy of tuberculosis.

Sandeep Tyagi, Nicole C. Ammerman, Si-Yang Li, John Adamson, Paul J. Converse, Rosemary V. Swanson, Deepak V. Almeida, and Jacques H. Grosseta

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19.01.15

Global biogeographic sampling of bacterial secondary metabolism

Charlop-Powers, Z., Owen, J. G., Reddy, B. V., Ternei, M. A., Guimaraes, D. O., de Frias, U. A., Pupo, M. T., Seepe, P., Feng, Z., & Brady, S. F.

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02.01.15

Broad and persistent Gag-specific CD8+ T-cell responses are associated with viral control but rarely drive viral escape during primary HIV-1 infection

Mopo Radebe, Kamini Gounder, Mammekwa Mokgoro, Zaza M. Ndhlovu, Zenele Mncube, Lungile Mkhize, Mary van der Stok, Manjeetha Jaggernath, Bruce D. Walker, Thumbi Ndung’u

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01.12.14

Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence

Rebecca Payne, Maximilian Muenchhoff, Jaclyn Mann, Hannah E. Roberts, Philippa Matthews, Emily Adland, Allison Hempenstall, Kuan-Hsiang Huang, Mark Brockman, Zabrina Brumme, Marc Sinclair, Toshiyuki Miura, John Frater, Myron Essex, Roger Shapiro, Bruce D. Walker, Thumbi Ndung'u, Angela R. McLean, Jonathan M Carlson, Philip J.R. Goulder

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10.09.14

Tuberculosis distorts the inhibitory impact of interleukin-10 in HIV infection.

Chetty S, Porichis F, Govender P, Zupkosky J, Ghebremichael M, Pillay M, Walker BD, Ndung'u T, Kaufmann DE, Kasprowicz VO.

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02.09.14

Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: Association with disease progression and influence of immune pressure.

Mann JK, Chopera D, Omarjee S, Kuang XT, Le AQ, Anmole G, Danroth R, Mwimanzi P, Reddy T, Carlson J, Radebe M, Goulder PJ, Walker BD, Abdool Karim S, Novitsky V, Williamson C, Brockman MA, Brumme ZL, Ndung'u T.

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27.08.14

Rapid sequencing of the Mycobacterium tuberculosis pncA gene for the detection of pyrazinamide susceptibility.

Streicher EM, Maharaj K, York T, Van Heerden C, Barnard M, Diacon A, Mendel CM, Bosman ME, Hepple JA, Pym AS, Warren RM, van Helden PD.

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26.08.14

Evaluation of the NucliSens EasyQ v2.0 Assay in Comparison with the Roche Amplicor v1.5 and the Roche CAP/CTM HIV-1 Test v2.0 in Quantification of C-Clade HIV-1 in Plasma

Muenchhoff M, Madurai S, Hempenstall AJ, Adland E, Carlqvist A, Moonsamy A, Jaggernath M, Mlotshwa B, Siboto E, Ndung'u T, Goulder PJ.

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