Centre for the AIDS Programme of Research in South Africa
Centre for the AIDS Programme of Research in South Africa (CAPRISA) is a multi-institutional AIDS research organisation that is undertaking globally relevant, locally responsive research that contributes to the understanding of HIV pathogenesis, prevention, and epidemiology, as well as the links between tuberculosis and HIV/AIDS. Led by K-RITH founding scientist and Columbia University professor Salim S. Abdool Karim, CAPRISA has five main research programmes: HIV pathogenesis, HIV vaccines, HIV and TB treatment, microbicides, and prevention and epidemiology. CAPRISA is a designated UNAIDS Collaborating Centre for HIV Prevention Research.
Founded by a Methodist missionary in 1855, Edendale Hospital is a 900-bed facility run by the Province of KwaZulu-Natal’s Department of Health. The teaching hospital opened in its current site, in Plessislaer, in 1954 and is a referral centre for people living in the surrounding area. The facility, a satellite campus for the Nelson R. Mandela School of Medicine, is involved in several major clinical trials in both HIV and TB.
HIV Pathogenesis Programme
HIV Pathogenesis Programme (HPP) is a research initiative established in 2002 at the University of KwaZulu-Natal in collaboration with Harvard Medical School. Led by K-RITH founding scientist and HHMI investigator Bruce Walker, HPP serves as a facility for both exploratory pathogenesis and translational research into HIV and tuberculosis, as well as a repository for samples collected from patients during HPP research studies. The laboratory has advanced equipment that makes cutting-edge research possible, including access to a Sanger sequencing facility. HPP was initially funded by the Doris Duke Charitable Foundation, but now attracts funding from other international and local funding agencies. HPP is also a branch of the Ragon Institute, which is a collaboration between Massachusetts General Hospital, the Massachusetts Institute of Technology, and Harvard.
Founded in 1909, McCord Hospital provides top quality, affordable healthcare for all population groups. The hospital is a centre for health education, training, and research both in Durban and internationally. In recent years, the hospital has been involved with groundbreaking clinical programmes and research in the field of HIV clinical care. It is especially known for its Anti Retroviral Treatment and Prevention of Mother to Child Transmission programmes, which have produced tremendous results and have attracted the attention of medical personnel and researchers from South Africa and around the world. McCord collaborates on research projects with Harvard University, Yale School of Medicine, and the Johns Hopkins School of Medicine.
The Nelson R. Mandela School of Medicine at the University of KwaZulu-Natal has produced almost 3,000 black African doctors and trained hundreds of students of all races to become medical specialists in many fields. During the past 10 years, under the leadership of K-RITH founding scientist and medical school dean Willem Sturm, the faculty has greatly increased its research capacity and has become a major player in HIV and tuberculosis research. In 2003, the Doris Duke Medical Research Institute was opened at the school, and its 14 specialist laboratories, which include a biosafety level 3 laboratory (also called a P3 laboratory), allows scientists to safely work with dangerous pathogens. The Nelson R. Mandela School of Medicine is celebrating its 60th anniversary in 2010.
Tugela Ferry Care and Research Collaboration
The Tugela Ferry Care and Research Collaboration (TF CARES) is an international nongovernmental organisation committed to improving prevention, care, and treatment for adults and children with HIV/AIDS and tuberculosis (TB) through clinical care, research and capacity building in Tugela Ferry, South Africa. The collaboration is housed at the Church of Scotland Hospital, a provincial government district hospital that serves 180,000 rural Zulu people with high rates of poverty and illiteracy. TF CARES has been providing care and treatment of patients with HIV and TB in the Tugela Ferry area since 1998. TF CARES’s goal is to improve patient care through the use of compassionate research, and it has made considerable inroads in areas such as community-based treatment, accelerated diagnostic tools, and infection control. The organisation collaborates with both Yale School of Medicine and the Albert Einstein College of Medicine.
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